Produced by Le Domaine de Rome de Bellegarde, the 1894 L’Eveil des Sens Cognac is made from four eaux de vie all aged over 70 years.
Only 67 bottles were ever created, with the spirit this year entering the Guinness Book of World Records after a 40ml measure was bought for £10,014.
The previous Guinness World Record for the most expensi ve Cognac sold was for £7,072 at the Inter Continental Hong Kong in 2016.
“This is an extremely exciting partnership for M and we can’t wait to start selling such an incredible cognac,” said M Restaurant director at Threadneedle Street, Zach Charilaou.
“Our members and regular diners at M are very distinguished regarding their drinks choices so I have no doubt that they will be keen to try Rome de Bellegarde.
"We offer members the option of purchasing their favourite spirits by the bottle, which we then keep locked away just for them.”
Guests at either the Victoria or Threadneedle sites of M Restaurant will be able to purchase either a 10ml shot for £2,514, or a one-litre decanter for £250,000.